ISIS Report 13/12/04
Cord Blood Stem Cells Mend Spinal Injury
Stem cells isolated from umbilical cord blood enable her to walk
again after 19 years. No need for embryonic stem cells.
Dr. Mae-Wan Ho reports
A patient who could not stand up for the past 19 years is now walking
after stem cells isolated from umbilical cord blood were injected into the
damaged areas of her spine.
The 37 year old woman received treatment from a team of Korean
researchers led by Prof. Song Chan-hun at Chosun University, Prof. Kang
Kyung-sun at Seoul National University and Dr. Han Hoon at Seoul Cord Blood
Bank. The researchers claimed they had performed a "miracle".
According to Prof. Song, the stem cells were transplanted on 12 October
2004, and in just three weeks, she started to walk with the help of a walker.
The patients legs were paralysed after an accident in 1985, which
damaged her lower back and hips, and since then, she was wheelchair bound.
The research team will test the efficacy of the new therapy on four
more patients as soon as they get clearance from the Chosun University ethics
board and the government, and will report their research to the scientific
world within the first half of the next year.
Songs colleagues Kang and Han stress the advantage of the new
treatment in avoiding the huge ethical problems of using human embryonic stem
cells that involves creating and destroying human embryos (see "No case for human embryonic stem
cells research", this series). Umbilical cord blood cells have been
routinely discarded after the birth of a baby in Korea.
The other advantages of using umbilical cord blood cells, according to
Kang and Han, are that, unlike embryonic stem cells, they do not give rise to
fatal teratomas (tumors containing jumbled up and disorganised cell types), and
being relatively immature cells, they do not trigger a big immune reaction, and
hence a strict cell type match is not required.
The Seoul Cord Blood Bank now retains blood from about 45 000 umbilical
cords, and are enough to cover all Koreans.
This story strikes yet another serious blow to those clamouring for
human embryonic stem cells research. But misinformation has already begun.
According to a report claiming to be from the editors of the
American Journal of Bioethics, the story is being trumpeted everywhere
as the research Reeve was pushing for, if only society would have allowed
it to go forward. Instead, the more likely "spin", it said, is just the
opposite; that the embryonic stem cells Reeve lobbied for wasnt what he
needed. Actor Christopher Reeve, who died recently, was paralysed after being
injured in an accident, and up until his death was lobbying for human embryonic
stem cells research which he hoped would cure people like him.
Astonishingly, these bioethicists end by stating that, "
the power of adult cells to heal cannot be fully explored without continuing
research on embryos at least for a few more years." Do they really understand
the science involved? Are they in the business to sow confusion among the
public and policy-makers?
Sources
"Korean scientists succeed in stem cell therapy" by Kim Tae-gyu, the
Korean Times 26 November 2004
http://times.hankooki.com/lpage/200411/kt2004112617575710440.htm
"Korean stem cell claims" 28 November 2004
http://blog.bioethics.net/2004/11/korean-stem-cell-claims.html
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