A group of 93 scientists from all over the world deplore the disinformation over the safety of GMOs and expose the lack of empirical and scientific evidence on which the false claims of “consensus” on safety are being made
Update 30/10/2013: The number of signatories has increased to 230 by 30 October, among them, Dr Belinda Martineau, who helped commercialise the world’s first GM food, the Flav Savr tomato. She says the debate on how to use this powerful GM technology safely is far from over. See full press release here: http://www.ensser.org/media/0613/
See the full list of signatories as of 30 October 2013 here: http://www.ensser.org/fileadmin/user_upload/131030_signatories_as_of_131030_lv.pdf
For a comprehensive report on hazards of GMOs see https://www.i-sis.org.uk/Ban_GMOs_Now.php
The full statement is reproduced below
As scientists, physicians, academics, and experts from disciplines relevant to the scientific, legal, social and safety assessment aspects of genetically modified organisms (GMOs) , we strongly reject claims by GM seed developers and some scientists, commentators, and journalists that there is a “scientific consensus” on GMO safety   and that the debate on this topic is “over”.
We feel compelled to issue this statement because the claimed consensus on GMO safety does not exist. The claim that it does exist is misleading and misrepresents the currently available scientific evidence and the broad diversity of opinion among scientists on this issue. Moreover, the claim encourages a climate of complacency that could lead to a lack of regulatory and scientific rigour and appropriate caution, potentially endangering the health of humans, animals, and the environment.
Science and society do not proceed on the basis of a constructed consensus, as current knowledge is always open to well-founded challenge and disagreement. We endorse the need for further independent scientific inquiry and informed public discussion on GM product safety and urge GM proponents to do the same.
Some of our objections to the claim of scientific consensus are listed below.
Regarding the safety of GM crops and foods for human and animal health, a comprehensive review of animal feeding studies of GM crops found “An equilibrium in the number [of] research groups suggesting, on the basis of their studies, that a number of varieties of GM products (mainly maize and soybeans) are as safe and nutritious as the respective conventional non-GM plant, and those raising still serious concerns”. The review also found that most studies concluding that GM foods were as safe and nutritious as those obtained by conventional breeding were “performed by biotechnology companies or associates, which are also responsible [for] commercializing these GM plants” .
A separate review of animal feeding studies that is often cited as showing that GM foods are safe included studies that found significant differences in the GM-fed animals. While the review authors dismissed these findings as not biologically significant , the interpretation of these differences is the subject of continuing scientific debate [8-11] and no consensus exists on the topic.
Rigorous studies investigating the safety of GM crops and foods would normally involve animal feeding studies in which one group of animals is fed GM food and another group is fed an equivalent non-GM diet. Independent studies of this type are rare, but when such studies have been performed, some have revealed toxic effects or signs of toxicity in the GM-fed animals [12-17]. The concerns raised by these studies have not been followed up by targeted research that could confirm or refute the initial findings.
The lack of scientific consensus on the safety of GM foods and crops is underlined by the recent research calls of the European Union and the French government to investigate the long-term health impacts of GM food consumption in the light of uncertainties raised by animal feeding studies [18, 19]. These official calls imply recognition of the inadequacy of the relevant existing scientific research protocols. They call into question the claim that existing research can be deemed conclusive and the scientific debate on biosafety closed.
It is often claimed that “trillions of GM meals” have been eaten in the US with no ill effects. However, no epidemiological studies in human populations have been carried out to establish whether there are any health effects associated with GM food consumption. As GM foods are not labelled in North America, a major producer and consumer of GM crops, it is scientifically impossible to trace, let alone study, patterns of consumption and their impacts. Therefore, claims that GM foods are safe for human health based on the experience of North American populations have no scientific basis.
Claims that there is a consensus among scientific and governmental bodies that GM foods are safe, or that they are no more risky than non-GM foods [20, 21], are false.
For instance, an expert panel of the Royal Society of Canada issued a report that was highly critical of the regulatory system for GM foods and crops in that country. The report declared that it is “scientifically unjustifiable” to presume that GM foods are safe without rigorous scientific testing and that the “default prediction” for every GM food should be that the introduction of a new gene will cause “unanticipated changes” in the expression of other genes, the pattern of proteins produced, and/or metabolic activities. Possible outcomes of these changes identified in the report included the presence of new or unexpected allergens .
A report by the British Medical Association concluded that with regard to the long-term effects of GM foods on human health and the environment, “many unanswered questions remain” and that “safety concerns cannot, as yet, be dismissed completely on the basis of information currently available”. The report called for more research, especially on potential impacts on human health and the environment .
Moreover, the positions taken by other organizations have frequently been highly qualified, acknowledging data gaps and potential risks, as well as potential benefits, of GM technology. For example, a statement by the American Medical Association’s Council on Science and Public Health acknowledged “a small potential for adverse events … due mainly to horizontal gene transfer, allergenicity, and toxicity” and recommended that the current voluntary notification procedure practised in the US prior to market release of GM crops be made mandatory . It should be noted that even a “small potential for adverse events” may turn out to be significant, given the widespread exposure of human and animal populations to GM crops.
A statement by the board of directors of the American Association for the Advancement of Science (AAAS) affirming the safety of GM crops and opposing labelling  cannot be assumed to represent the view of AAAS members as a whole and was challenged in an open letter by a group of 21 scientists, including many long-standing members of the AAAS . This episode underlined the lack of consensus among scientists about GMO safety.
An EU research project  has been cited internationally as providing evidence for GM crop and food safety. However, the report based on this project, “A Decade of EU-Funded GMO Research”, presents no data that could provide such evidence, from long-term feeding studies in animals.
Indeed, the project was not designed to test the safety of any single GM food, but to focus on “the development of safety assessment approaches” . Only five published animal feeding studies are referenced in the SAFOTEST section of the report, which is dedicated to GM food safety . None of these studies tested a commercialised GM food; none tested the GM food for long-term effects beyond the subchronic period of 90 days; all found differences in the GM-fed animals, which in some cases were statistically significant; and none concluded on the safety of the GM food tested, let alone on the safety of GM foods in general. Therefore the EU research project provides no evidence for sweeping claims about the safety of any single GM food or of GM crops in general.
A frequently cited claim published on an Internet website that several hundred studies “document the general safety and nutritional wholesomeness of GM foods and feeds”  is misleading. Examination of the studies listed reveals that many do not provide evidence of GM food safety and, in fact, some provide evidence of a lack of safety. For example:
Environmental risks posed by GM crops include the effects of Bt insecticidal crops on non-target organisms and effects of the herbicides used in tandem with herbicide-tolerant GM crops.
As with GM food safety, no scientific consensus exists regarding the environmental risks of GM crops. A review of environmental risk assessment approaches for GM crops identified shortcomings in the procedures used and found “no consensus” globally on the methodologies that should be applied, let alone on standardized testing procedures .
Some reviews of the published data on Bt crops have found that they can have adverse effects on non-target and beneficial organisms [42-45] – effects that are widely neglected in regulatory assessments and by some scientific commentators. Resistance to Bt toxins has emerged in target pests , and problems with secondary (non-target) pests have been noted, for example, in Bt cotton in China [47, 48].
Herbicide-tolerant GM crops have proved equally controversial. Some reviews and individual studies have associated them with increased herbicide use [49, 50], the rapid spread of herbicide-resistant weeds , and adverse health effects in human and animal populations exposed to Roundup, the herbicide used on the majority of GM crops [52-54].
As with GM food safety, disagreement among scientists on the environmental risks of GM crops may be correlated with funding sources. A peer-reviewed survey of the views of 62 life scientists on the environmental risks of GM crops found that funding and disciplinary training had a significant effect on attitudes. Scientists with industry funding and/or those trained in molecular biology were very likely to have a positive attitude to GM crops and to hold that they do not represent any unique risks, while publicly-funded scientists working independently of GM crop developer companies and/or those trained in ecology were more likely to hold a “moderately negative” attitude to GM crop safety and to emphasize the uncertainty and ignorance involved. The review authors concluded , “The strong effects of training and funding might justify certain institutional changes concerning how we organize science and how we make public decisions when new technologies are to be evaluated.”
The Cartagena Protocol on Biosafety was negotiated over many years and implemented in 2003. The Cartagena Protocol is an international agreement ratified by 166 governments worldwide that seeks to protect biological diversity from the risks posed by GM technology. It embodies the Precautionary Principle in that it allows signatory states to take precautionary measures to protect themselves against threats of damage from GM crops and foods, even in case of a lack of scientific certainty .
Another international body, the UN's Codex Alimentarius, worked with scientific experts for seven years to develop international guidelines for the assessment of GM foods and crops, because of concerns about the risks they pose. These guidelines were adopted by the Codex Alimentarius Commission, of which over 160 nations are members, including major GM crop producers such as the United States .
The Cartagena Protocol and Codex share a precautionary approach to GM crops and foods, in that they agree that genetic engineering differs from conventional breeding and that safety assessments should be required before GM organisms are used in food or released into the environment.
These agreements would never have been negotiated, and the implementation processes elaborating how such safety assessments should be conducted would not currently be happening, without widespread international recognition of the risks posed by GM crops and foods and the unresolved state of existing scientific understanding.
Concerns about risks are well-founded, as has been demonstrated by studies on some GM crops and foods that have shown adverse effects on animal health and non-target organisms, indicated above.Many of these studies have, in fact, fed into the negotiation and/or implementation processes of the Cartagena Protocol and Codex. We support the application of the Precautionary Principle with regard to the release and transboundary movement of GM crops and foods.
In the scope of this document, we can only highlight a few examples to illustrate that the totality of scientific research outcomes in the field of GM crop safety is nuanced, complex, often contradictory or inconclusive, confounded by researchers’ choices, assumptions, and funding sources, and in general, has raised more questions than it has currently answered.
Whether to continue and expand the introduction of GM crops and foods into the human food and animal feed supply, and whether the identified risks are acceptable or not, are decisions that involve socioeconomic considerations beyond the scope of a narrow scientific debate and the currently unresolved biosafety research agendas. These decisions must therefore involve the broader society. They should, however, be supported by strong scientific evidence on the long-term safety of GM crops and foods for human and animal health and the environment, obtained in a manner that is honest, ethical, rigorous, independent, transparent, and sufficiently diversified to compensate for bias.
Decisions on the future of our food and agriculture should not be based on misleading and misrepresentative claims that a “scientific consensus” exists on GMO safety.
Article first published 21/10/13
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Robin Gaura Comment left 22nd October 2013 01:01:18
Thanks for the info, I love your site. I have referenced it in my letter to the California Public Safety Commission hearings today which relate specifically to prisoner health and safety. My contention is that the processed foods diet given incarcerated people in California is a cause of the high cost of degenerative diseases and medical treatments given especially the aging population. I especially reference studies on glyphosate, as gut dysbiosis is an apparent cause of so many degenerative diseases. Best Wishes, Robin
DR. SEE Comment left 24th October 2013 06:06:21
This type of information should be made known to the people of all nations especialy to the key leaders. I will try my best to let my friends know about this.
Sharmin Ahmad Comment left 24th October 2013 06:06:17
This article is a must read for everyone who cares for environment, health and safety. More discussion on this important topic should be conducted for public aareness. Many thanks for sharing this article.
Douglas Hinds Comment left 29th October 2013 02:02:27
I must disagree: While to it is true that no consensus exists to the effect that GM Crops and Foods are in fact safe for the environment and consumer's health, sufficient evidence HAS accumulated to safely consider the following statements to be established, adequately documented facts: 1.- The Conceptual Basis underlying Genetic Modification is False! Because DNA is NOT a blueprint for predictable genetic behavior or protein fabrication. Other factors not taken into account by the biotech industry are present and furthermore, changes to the structure of the original genome generated by the mechanisms employed to insert the transgene packages into the host organism often alter the structure of original genome, and neither of these proven phenomena are either taken into account, or investigated by the biotech industry. See: "Unraveling the DNA Myth: The Spurious Foundation of Genetic Engineering" by Barry Commoner: https://www.commondreams.org/views02/0209-01.htm and "The Fluid Genome and Beyond" by Mae-Wan Ho: http://www.i-sis.org.uk/Fluidgenomeandbeyond.php 2.- The methods employed to insert normally (evolutionarily) incompatible genes into a preexisting host's genome are derived from either invasive pathological organisms or imprecise mechanical "gene guns", neither of which can be programmed to insert the "desired" (arbitrarily selected), normally incompatible gene packages into a definable location with any reliable degree of accuracy. 3.- As stated above, the results of introducing arbitrary packages of individual genes (rather than the much more orderly, balanced and time tested process of gametic reproduction, which evolved over millenniums) can not be predicted via currently available scientific methods, and the biotech industry doesn't even bother to investigate these phenomena, which never-the-less, have been demonstrated to occur. In conclusion, the technology is currently impossible to control and at present, the results are still impossible to predict. 4.- Given the above, GM organisms are obviously NOT Substantially Equivalent to Conventionally derived seeds and that apocryphal classification was applied erroneously, in response to the interested parties own economic interests and desire to evade the comprehensive scrutiny that all new pharmacological products are subjected to. 5.- The claims regarding the supposed benefits of GM Seeds made by the biotech industry have not been substantiated in practice: GM Crops do NOT require fewer agrochemicals, do NOT produce larger harvests and ARE both more costly and more prone to crop failure. (See Charles Benbrook's study): http://organic-center.org/reportfiles/GE13YearsReport.pdf 6.- The behavior demonstrated by the owner's of the patented gene's in courts of law strongly suggests that rather than provide farmers with a reliable and cost effective technology or assure a sufficient supply of nutritious and safe food for consumers, the motivation for creating GM Seeds is to OWN a patent, corner a captive market and create a permanent state of farmer dependency on their own proprietary chemical products. (The majority of the world's seed producers were purchased by the chemical manufacturing companies). 7.- Furthermore: In order to accomplish those goals, the biotech industry has infiltrated the governmental agencies created to protect the environment and public health in the countries they have targeted for commercializing their products, unduly influenced legislators, the mass media, professional trade journals and research institutions via contributions and failing that, via threats and attacks, whenever their methods, the nature of their products or the results of their research are called into question. In Conclusion: If a consensus does in fact exist, it is certainly NOT favorable to the safety or innocuousness of the presence of Genetically Modified Organisms in the open environment and international food supply but rather, quite the contrary. All available indicators point to the existence of a gigantic fraud perpetrated on the public by a an unethical, immoral and economically motivated group of corporate players, to the detriment of society itself.
Paulo Andrade Comment left 29th October 2013 02:02:42
Indeed, there is no need for consensus as both science and risk assessment are based on majority opinion. Please have a look at http://genpeace.blogspot.com.br/2013/10/no-need-for-scientific-consensus-on-gmo.html
Flavio Togni Ferreira Comment left 28th November 2013 08:08:16
The GM crops are a huge fraud. They are a risc to the environment and to the human health. They dont yield better nor are more profitable. Brazilian mass media ignores the issue and prevents that a free discussion take place. Unlike in neighboring Argentina discussions arrived at Congress. The studies of Dr. Carrasco is a proof of the damage they can cause to health. See below https://www.youtube.com/watch?v=z2EI9NliNt4 http://www.gmwatch.org/files/GMsoy_SustainableResponsible_Sept2010_Summary.pdf